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SKC Bridges the Gap for Innovative Researcher in 2010

February 25, 2010

Unfortunately, promising research ideas are often hindered from the clinic not from scientific merit but from politics and bureaucracy. Solving Kids' Cancer is very pleased to be able to provide "bridge funding" to Cincinnatti Children's Hospital and pediatric oncologist/investigator Timothy Cripe, MD, PhD.

Dr. Cripe is one of the leading experts in the use of innovative biotherapeutics, specifically oncolytic viruses. In 2008, Dr. Cripe and his team submitted a grant to the FDA's Orphan Drug Development Program to fund a promising clinical trial using the HSV-1 oncolytic virus for pediatric solid tumors. The agency scored the grant proposal very high which meant it would be fundable within the next cycle of government funding. Dr. Cripe and his colleagues proactively prepared to have the trial ready to launch by gaining all approvals and securing logistics. Months went by and the agency stated that it had to wait until the next federal budget was approved. In February 2010, the agency informed the Cincinnati team that the grant was still approved but funding would be further delayed until the end of 2010 due to the need to use their current funding for other priorities.

Upon the news, SKC interceded and awarded Dr. Cripe and his institution enough funding to start this innovative trial in the first quarter of 2010 and enroll the first 3 patients. SKC continues to strive toward providing vitally needed new therapeutic options for children with cancer and to identify/remove barriers that stand in the way.