TWiPO #68 – Interview with Dr. Dean Lee

Hosts Dr. Timothy Cripe and Dr. Nilay Shah, from Nationwide Children’s Hospital in Columbus, Ohio, are joined by Dr. Dean Lee to discuss their experience with T-cell CARs (Chimeric Antigen Receptors).  T-cell CARs enable researchers to essentially train one’s immune system to recognize a specific protein that is on a virus or disease.  In the case of CARs, researchers have learned how to “ad on” a receptor that enables T-cells to also recognize very specific proteins found on a particular type of cancer cell.  We have seen incredible results using T-cell CARs in children with Acute Lymphoblastic Leukemia (ALL) and we hope those findings can soon translate into new, effective T-cell CARs that can recognize other types of pediatric cancers, as well.  Listen now to learn more.

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